http://ifttt.com/images/no_image_card.png
The Canadian researchers revealed the genetic fingerprint that leads to a deeper understanding as to why there are 30 percent of men with curable localized prostate cancer that end up with the aggressive disease post radiotherapy or surgery.
These results prove to be important as these could potentially lead to other targeted therapies. Medical practitioners can customize the form of treatment for their patients. This can have a positive and effective outcome from the moment of diagnosis. This is according to co-principal investigator Robert Bristow, a Professor in the Departments of Radiation Oncology and Medical Biophysics, University of Toronto.
The research team comprised of Dr. Bristow, co-principal investigator Dr. Paul Boutros from the Ontario Institute for Cancer Research, lead author Dr. Michael Fraser, and collaborators at Laval University in Quebec City, examined the tumors of 500 Canadian men from the general population. They have localized and non-inherited prostate cancer.
Prostate Cancer Researchers Find Genetic Fingerprint Identifying How, When Disease Spreads
Canadian prostate cancer researchers have discovered the genetic fingerprint that explains why up to 30 per cent of men with potentially curable localized prostate cancer develop aggressive disease that spreads following radiotherapy or surgery. Read more…
The selected men were treated with surgery or radiation. The team analyzed the genetic make-up of their tumors to check if there was a connection between the men who had good results from treatment and those who did not.
Metro News Canada highlights the reason why this discovery is quite vital in cancer research: it means that doctors have a higher chance of discovering the disease in the early stages. Dr. Bristow said that they utilized special DNA sequencing techniques in order to identify the genetics of prostate cancers. This enables them to understand the differences between one man’s disease to another.
The fingerprints have a higher accuracy in determining men who respond well to surgery or radiotherapy as well as those who have had the disease metastasize outside of the prostate gland. The information leads to clues how clinicians can treat one set of men versus the other to increase cure rates in general.
Researchers Discover Genetic Fingerprint Identifying How Prostate Cancer Spreads
The discovery means doctors may be able to predict at an early stage whether a prostate tumour will become aggressive and potentially deadly, allowing for more personalized treatment from the moment a man is diagnosed, said co-principal investigator Dr. Robert Bristow, a clinician-scientist at Princess Margaret Cancer Centre in Toronto. Read more…
Calgary Herald talks about why these patients can’t simply have radiotherapy or surgery alone. The patients should also have some sort of chemo or hormonal therapy because the cancer cells had spread throughout the body.
In Canada, this type of cancer is the most common among men. It is also the third leading cause of male cancer death after lung and colorectal cancers. Around 21,600 Canadian men were diagnosed with prostate CA in 2016, and 4,000 died because of the disease.
The Toronto team collaborated with Monash University in Melbourne, Australia on a related study. The analysis showed that prostate tumors are related to the inherited BRCA2 gene mutation. It gets lethal: kills about half of patients within five years of diagnosis.
Researchers Discover Genetic Fingerprint Identifying How Prostate Cancer Spreads
In a related study published Monday in Nature Communications, the Toronto researchers and collaborators at Monash University in Melbourne, Australia, were able to show through genetic analysis why prostate tumours linked to the inherited BRCA2 gene mutation turn lethal, killing half of affected patients within five years of diagnosis. Read more…
Every year, more and more people fall into the hands of this disease. If the team can procure a great outcome for future techniques related to genetic fingerprinting, this would truly be beneficial in the field of Oncology.
The post Cancer Researchers Find Genetic Fingerprint Which Alerts Prostate Cancer Growth appeared first on NUTRITION CLUB CANADA.
from NUTRITION CLUB CANADA http://nutritionclub.ca/genetic-fingerprint/amp/
from Nutrition Club http://nutritionclub.tumblr.com/post/155686585318
from Tumblr http://vincentpennington.tumblr.com/post/155686619084
No comments:
Post a Comment